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. 2015 Dec 14;5:18110. doi: 10.1038/srep18110

Table 1. Ion channels, transporters, and exchangers that were identified in the human ES by LC-MS/MS.

Accession number Description (gene name) Max coverage (%) Max protein score
gi|6090615 dihydropyridine receptor alpha 2 subunit (CACNA2D1) 13.7 83
gi|38505268 voltage-dependent T-type calcium channel subunit alpha-1G isoform 14 (CACNA1G) 10.5 72
gi|7630181 alpha1A-voltage-dependent calcium channel (CACNA1A) 3.6 70
gi|292275 L-type voltage-dependent calcium channel (CACNA1) 6.1 66
gi|179764 calcium channel alpha-1D subunit (CACNA1D) 6.2 64
gi|20070163 voltage-dependent T-type calcium channel subunit alpha-1G isoform 1 (CACNA1G) 8.5 63
gi|5565888 T-type calcium channel alpha1I subunit (CACNA1I) 4.7 56
gi|14336738 voltage dependent t-type calcium channel alpha-1H subunit (CACNA1H) 5.4 52
gi|443761 voltage-operated calcium channel; alpha-1 subunit (CACNA1E) 7.2 54
gi|7159257 calcium channel alpha1E subunit; delta39 splice variant (CACNA1E) 10 56
gi|9711929 alpha1A-voltage-dependent calcium channel (CACNA1A) 10.3 55
gi|3183953 L-type calcium channel alpha-1 subunit (CACNA1F) 3.7 54
gi|55962840 calcium channel; voltage-dependent; N type; alpha 1B subunit (CACNA1B) 5.3 51
gi|4336152 low-voltage activated calcium channel alpha (CACNA1H) 4.9 51
gi|179762 calcium channel alpha-2b subunit (CACNA2D1) 7.1 51
gi|495868 voltage-dependent calcium channel alpha-1E-1 (CACNA1E) 5.6 50
gi|62088514 calcium channel; voltage-dependent; L type; alpha 1B subunit variant (CACNA1B) 11 46
gi|21314671 transient receptor potential cation channel subfamily M member 4 isoform 1 (TRPM4) 15.8 52
gi|54632969 long transient receptor potential channel 3 (TRPM3) 3.3 52
gi|76780233 TRPC4 protein (TRPC4) 5.4 54
gi|194733735 short transient receptor potential channel 3 isoform a (TRPC3) 7.9 47
gi|24119274 sodium leak channel non-selective protein (NALCN) 8.9 65
gi|189047 Na+ channel (SCN7A) 3.1 59
gi|25014054 RecName: Full = Sodium channel protein type 3 subunit alpha; AltName: Full = Sodium channel protein brain III subunit alpha; (AltName: Full = Sodium channel protein type III subunit alpha; AltName: Full = Voltage-gated sodium channel subtype III; AltName: Fu (SCN3A) 4.8 45
gi|6693697 voltage-gated sodium channel alpha subunit SCN12A (SCN12A) 6.9 45
gi|10334701 apamin-sensitive small-conductance Ca2+-activated potassium channel (KCNN2) 7.4 57
gi|186798 voltage-gated potassium channel (KCNB1) 10.1 54
gi|338077 potassium channel protein (KCNC4) 6.4 53
gi|27437001 potassium voltage-gated channel subfamily H member 1 isoform 1 (KCNH1) 10 49
gi|21361181 sodium/potassium-transporting ATPase subunit alpha-1 isoform a (ATP1A1) 9.1 66
gi|497763 Na+; K+ -ATPase catalytic subunit (ATP1A3) 5.4 45
gi|14286105 RecName: Full = Plasma membrane calcium-transporting ATPase 4; Short = PMCA4; AltName: Full = Matrix-remodelling-associated protein 1; AltName: Full = Plasma membrane calcium ATPase isoform 4; AltName: Full = Plasma membrane calcium pump isoform 4 (ATP2B4) 14.9 53
gi|118498343 calcium-transporting ATPase type 2C member 2 (ATP2C2) 13 48
gi|17865805 sodium/calcium exchanger 3 isoform B precursor (SLC8A3) 5.3 50
gi|15147254 sodium/calcium exchanger 3 isoform A precursor (SLC8A3) 9 46
gi|4505697 Pendrin (SLC26A4) 6 44
gi|68534512 Anoctamin 6 (ANO6) 8.7 52

Proteins searched through MASCOT (version 2.2.07) against the NCBInr database. The search parameters were: 1) Enzyme specificity - Trypsin; 2) Maximum missed cleavages - 2; 3) Carbamidomethyl (C); Oxidation (M) as variable modifications.