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. 2015 Oct 31;6(12):1209–1214. doi: 10.1021/acsmedchemlett.5b00359

Figure 3.

Figure 3

Effect of intrathecal (i.t.) administration of morphine (M), 12, 13, and the parent NK1 antagonist 5 as measured in the tail flick-test 30 min after administration in naïve rats; ***p < 0.001 vs vehicle (Veh)-treated naïve rats.