. 2015 Oct 23;6(12):1225–1230. doi: 10.1021/acsmedchemlett.5b00364

Table 1. Biochemical Activities of p97 Inhibitors^a.

entry	compound/R-group	p97-ADPGlo IC₅₀ [μM]	p97-ADPGlo Std. Dev. [μM]
1	12/CF₃	4.7	±2.0
2	13/SF₅	21.5	±0.4
3	23/NO₂	0.05	±0.04
4	24/CH₃	0.24	±0.11
5	25/OCH₃	0.71	±0.22
6	26/OCF₃	3.8	±0.8

Assay conditions: ADPGlo with 20 nM p97 ATPase WT in the presence of 100 μM ATP.³⁷ Assays were run in quadruplicate (12, 13, 25, 26), seven times (24), or nine times (23).

Table 1. Biochemical Activities of p97 Inhibitorsa.

Table 1. Biochemical Activities of p97 Inhibitors^a.