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. 2015 Dec 14;5:18215. doi: 10.1038/srep18215

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Copyright © 2015, Macmillan Publishers Limited

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HepG2 cells were incubated in the presence or absence of catalase for 1 h, treated with Akbu-LAAO or exogenous H₂O₂ for 24 h and stained Hoechst 33258. Nuclear condensation and/or fragmentation represent cell apoptosis. Images were taken at a magnification of 200×. Arrows marked the apoptotic cells for representing nuclear condensation/fragmentation.