Table 4.

LOO AUC estimation of the classifiers on the various combinations of features for each classification contrast.

		CART	RF	SVM (rbf)	SVM (lin)
LOBD vs. AD	1. BIO	45.78	59.21	71.28	61.19
	2. NEURO	66.60	71.28	68.58	55.15
	3. BEHAV	85.64	83.87	79.81	83.87
	4. BIO + NEURO	66.39	61.91	70.86	66.60
	5. BIO + BEHAV	79.81	73.35	80.03	79.81
	6. NEURO + BEHAV	80.24	80.74	82.73	84.08
	7. NEURO + BEHAV + BIO	78.67	79.39	84.50	82.73
	8. NEURO + BEHAV + BIO-Wt	89.57	86.39	88.25	87.33
HC vs. AD	1. BIO	70.53	57.07	55.51	47.61
	2. NEURO	88.25	92.88	87.47	84.20
	3. BEHAV	95.37	95.37	94.02	94.80
	4. BIO + NEURO	84.98	87.47	87.47	88.83
	5. BIO + BEHAV	92.10	91.53	96.73	93.45
	6. NEURO + BEHAV	93.45	96.73	95.37	96.15
	7. NEURO + BEHAV + BIO	95.37	95.37	95.95	92.67
	8. NEURO + BEHAV + BIO-Wt	97.33	98.17	98.17	97.77
HC vs. LOBD	1. BIO	45.79	47.72	53.12	59.01
	2. NEURO	76.32	77.16	79.45	82.93
	3. BEHAV	89.54	89.90	91.47	91.11
	4. BIO + NEURO	79.81	82.57	77.88	77.88
	5. BIO + BEHAV	82.57	93.03	91.47	91.47
	6. NEURO + BEHAV	82.93	94.23	93.75	93.39
	7. NEURO + BEHAV + BIO	82.57	89.18	93.75	91.83
	7. NEURO + BEHAV + BIO-Wt	91.37	96.38	95.55	95.55

Bold values are the maximum attained by a classifier per classification contrast.

BIO, blood biomarkers; BEHAV, clinical variables; NEURO, neuropsychological tests; Wt variables selected according to Welch’s t-test.