Histological analysis of spared tissue. (A) Heat maps showing the void (yellow-red) and gray matter (green-blue) for all animals sliced in the coronal plane. Color denotes injury extent in the rostro-caudal dimension, and animals are arranged by injury void area. Rostral-caudal extent of (B) void area per slice, (C) ipsilateral gray matter sparing, and (D) ipsilateral white matter sparing. Arrow in B highlights greater rostral void following 0.8 mm injury. All data are normalized to the slice with the largest area on the contralateral side, except for the void volume (mean±standard error of the mean). Bar graphs summarize the average value of each measure for tissue from the epicenter±2.4 mm (mean±standard error of the mean; * denotes p<0.05; intact, n=4; sham, n=4; 0.6 mm n=5; 0.8 mm, n=6). Color image is available online at www.liebertpub.com/neu