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Evaluation of clonal contribution. The clonal frequency was determined using the span count percentage. All data points represent a single retroviral integration site (RIS), identified in triplicate samples, and are presented with standard error. (A) Lentiviral-mutagenized samples exhibiting clonal expansion, (B) oligoclonal gamma retroviral-mutagenized samples, and (C) polyclonal foamy virus vector-mutagenized samples.
