Table 1.
Characteristics of Patients With Candida glabrata Candidemia by Echinocandin Susceptibility
| Characteristic | Echinocandin Nonsusceptible, n (%) | Echinocandin Susceptible, n (%) | P Valuea |
|---|---|---|---|
| Total: n = 1334 | 83 (6.0) | 1302 (94.0) | <.001 |
| Age in years | |||
| 0–1 | 0 (0) | 15 (1.2) | |
| 2–17 | 2 (2.4) | 7 (0.5) | |
| 18–44 | 28 (33.7) | 187 (14.5) | |
| 45–64 | 25 (30.1) | 531 (41.1) | |
| ≥65 | 28 (33.7) | 552 (42.7) | |
| Female sex | 39 (47.6) | 675 (52.0) | .494 |
| Black race | 43 (54.4) | 688 (54.9) | >.999 |
| Underlying liver condition | 10 (12.1) | 191(14.7) | .630 |
| Diabetes | 35 (42.2) | 525 (40.3) | .731 |
| Abdominal surgery in the 90 days prior to candidemia | 18 (21.7) | 252 (19.4) | .668 |
| Previous hospitalization in the 90 days prior to candidemia | 65 (78.3) | 729 (59.1) | <.001 |
| Nursing home resident at the time of candidemia | 23 (30.3) | 293 (25.5) | .347 |
| Intensive care unit admission for candidemia | 51 (62.2) | 815 (64.1) | .723 |
| Central venous catheter present in the 2 days prior to candidemia | 70 (86.4) | 947 (76.8) | .054 |
| Total parenteral nutrition in the 14 days prior to candidemia | 34 (41.0) | 350 (26.9) | .008 |
| Previous candidemia episode | 33 (40.2) | 98 (7.6) | <.001 |
| Ever received echinocandin | 32 (38.6) | 68 (5.2) | <.001 |
| Fluconazole-resistant isolate | 27 (32.9) | 105 (8.1) | <.001 |
| Number of days in the hospital before candidemia, median (IQR) | 7 (0–15) | 5 (0–20.5) | .303b |
| Death within 30 days of candidemia | 18 (21.7) | 357 (27.5) | .308 |
The significant P Values are indicated in bold.
Abbreviation: IQR, interquartile range.
a Fishers exact test.
b Wilcoxon rank-sum test.