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. 2015 Dec 7;10:7333–7343. doi: 10.2147/IJN.S92099

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© 2015 Han et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Histological visualization of interface between autologous tendon and host bone 4 or 8 weeks after ACL surgery in a rabbit model.

Notes: (A and C) PCL/nHAp/Col-treated tendon group. (B and D) Non-treated autologous tendon group as a control. (H&E staining, ×200 magnification). Some inflammatory cells were observed at 4 weeks (white arrows). In PCL/nHAp/Col group, new bone growth into the interface was observed 8 weeks after surgery (black arrows). Scale bar =200 µm.

Abbreviations: ACL, anterior cruciate ligament; Col, collagen; H&E, hematoxylin and eosin; HB, host bone; G, autologous tendon graft; IF, interface; nHAp, nanohydroxyapatite; PCL, polycaprolactone.