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(A) Schematic illustration of the human mtDNA region downstream of LSP promoter. The numbers below the scheme corresponds to the reference human mtDNA; the transcribed sequence of CSBII is shown at the top. (B) MtRNAP does not terminate at CSBII in the presence of TEFM. Termination efficiency (%) is indicated below the panel. (C) A rare polymorphism in a reference mtDNA results in a decreased efficiency of transcription termination at CSBII.
