Table 4.

Room temperature cross-couplings with reversal of polarity in coupling partners

Conditions(a): Aryl-X (0.5 mmol, 1.0 equiv), Ar’-Bpin (0.53 mmol, 1.05 equiv). Sequence of addition-mixing of 16 or 17 with MeMgBr (1:1) for 1 min at RT under Ar followed by sequential addition of Aryl-X with 30 sec of stirring, K₃PO₄ (0.18 mmol, 0.35 equiv), and Ar-Bpin. Note: For Ar-HetAr’ or HetAr-Ar’ systems 1.5 mmol of 16; HetAr-HetAr’: 1.0 mmol of 16, and for Ar-Ar’ systems: 3 mmol 17 was employed as pre-catalyst.