Table 3.
Summary of epidemiology, phenomenology and treatment in this study, in primary bowing tremor (PBT) and primary writing tremor (PWT)
| Mean age at onset (yrs) | SD of onset age (yrs) | Sample size | Type B | Alcohol responsive | Antichol | Dosage per day | Prop | Dosage per day | Prim | Dosage per day | BTX | Dosage per day | Family history | Trauma | Tremor frequency (Hz) | Ratio f:m | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TST in musicians | |||||||||||||||||
| This paper | 51.5 | 11.4 | n = 23 | 10 (43%) | 6/18 (33%) | 2/10 (20%) | 6 mg | 9/15 (60%) | 5-80 mg | 3/4 (75%) | 60 mg | 4/5 (80%) | 5-23.4 U/m | 9 (39%) | 9 (39%) | 6.5 (+ − 0.9) | 4:19 |
| PBT | |||||||||||||||||
| Lederman [2] | 41 | 23.2 | n = 5 | 2 (40%) | 1/1 (100%) | 0/1 | 6 mg | 1/1 (100%) | 20 mg | - | - | - | - | 2 (40%) | - | - | 3:02 |
| PWT | |||||||||||||||||
| Rosenbaum & Jankovic [7] | 50.5 | 14.8 | n = 10 | 3 (30%) | 2/4 (50%) | 4/5 (80%) | - | 4/4 (100%) | - | - | - | - | - | 3 (30%) | - | - | 3:07 |
| Bain et al. [5] | 50.1 | range (16–76) | n = 21 | 10 (48%) | 7/17 (41%) | 4/12 (33%) | - | 4/12 (33%) | - | 3/4 (75%) | 62.5-125 mg | 2/2 (100%) | 33 U/m | 7 (33%) | 4 (19%) | 5.5 (4.1-7.3) | 1:20 |
| Kachi et al. [6] | 40.8 | 18.1 | n = 10* | 3 (30%) | 3/4 (75%) | - | - | 10/11 (91%)# | 120-240 mg+ | - | - | - | - | 0 | 3 (30%) | 5-Jun | 2:08 |
| Elble et al. [8] | 37 | 13.9 | n = 5 | 2 (40%) | 1/4 (25%) | 1/3 (33%)## | 12-15 mg++ | 0/3 (0%) | 240 mg | 0/2 (0%) | 750 mg | - | - | 1 (20%) | - | 5-Jul | 1:04 |
| Modugno et al. [12] | 51.7 | 16.2 | n = 7 | 1 (14%) | - | - | - | - | - | - | - | - | - | 3 (43%) | - | 5-Jul | 1:06 |
| Ondo & Satija [19] | 47.2 | 18 | n = 56 | 11 (20%) | - | - | - | 31** | - | 18** | - | 17** | - | 27 (48%) | - | - | 41:15:00 |
| Papapetropoulos & Singer [14] | 48.4 | 15.5 | n = 5 | 2 (40%) | 0/5 | 1/2 (50%) | 6 mg | - | - | - | - | 4/4 (100%) | 10-12.5 U/m | 0 | - | - | 2:03 |
*One patient had golfing tremor; # in five patients propranolol was administered intravenously and not orally, of whom 4 resonded; +only orally administered propranolol; ##2xtrihexyphenidyl, 1xbenztropine (no effect); ++dosage only for trihexyphenidyl; **only the number of treated patients was reported with a mean rating of success; ## not includeing the range given by Bain et al. Abbreviations: TST Task-specific tremor, PBT Primary bowing tremor, PWT Primary writing tremor, yrs years, SD standard deviation, Type B type B task-specific tremor, Antichol anticholinergic medication, Prop propranolol, Prim primidone, f female, m male, appr approximately.
For the treatment and alcohol responsiveness, the numerator indicates positive response to the respective medication/alcohol whereas the denominator indicates the number of patients treated with the respective medicament/alcohol in the respective study.