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Changes in mean arterial blood pressure of rats treated with POPi. Arterial blood pressure was monitored and changes in mean arterial pressure plotted during bolus injections of bradykinin (A) or angiotensin I (B) in rats treated long-term with vehicle (peanut oil), S17092 (40 mg/kg per day), or captopril (100 mg/kg per day). **P<0.01 and *P<0.05. Data are expressed as mean±SE.
