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. 2014 Aug 21;26(1):180–191. doi: 10.1093/cercor/bhu190

Figure 2.

Figure 2.

D4R agonist PD168077 induced different effects on sAP frequency in PFC pyramidal neurons and PV+ interneurons. (A) The time course of normalized sAP frequency showing the effect of PD168077 (40 μm) in PFC pyramidal neurons (triangle unfilled) and PV+ interneurons (round filled). (B,C) Representative traces of sAP at different time points (denoted by ad) in plot A. Scale bars: 20 mV, 1 s. (D) Dose–response data and fitted curves showing the percentage changes in sAP frequency by different concentrations of PD168077 in PFC pyramidal neurons and PV+ interneurons. *P < 0.01.