Table 1.
Biochemical parameter | Treatment | |||
---|---|---|---|---|
Control | Placebo | SOD1 | Nanozyme | |
Total protein concentration, mg/mL | 2.2 ± 0.3 | 19.3 ± 3.2 | 15.6 ± 2.3 | 10.5 ± 1.1∗∗ |
α 2-Macroglobulin, arb. U/mL | 0.6 ± 0.1 | 10.8 ± 1.0 | 8.7 ± 1.5 | 7.2 ± 1.6∗ |
Antioxidant activity, U/mL | 14.4 ± 1.0 | 2.3 ± 0.9 | 3.3 ± 0.6 | 3.7 ± 0.2 |
SOD1 activity, trolox-equivalents/mL | 280 ± 40 | 460 ± 100 | 370 ± 80 | 330 ± 50∗ |
∗Significant difference between nanozyme and placebo by the Mann-Whitney U test, p < 0.05; ∗∗Significant difference between nanozyme and placebo, and nanozyme and native SOD1 by the Mann-Whitney U test, p < 0.01.