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Effect of ISC-SN on INS-1 cell apoptosis. (a) Cell apoptosis was determined by PI staining (red), (b) PI-staining index, and (c) caspase-3 activity in INS-1 cells cultured with ISC-SN for 48 h. Data are expressed as mean ± SE (n = 3), ∗∗ P < 0.01.
