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. 2014 Aug 2;2:22. doi: 10.1186/s40635-014-0022-1

Figure 5.

Figure 5

sRAGE in lung lavage fluid in 1-hit VILI. Soluble RAGE (sRAGE) levels in bronchoalveolar lavage fluid (BALF) of wild-type (WT) mice ventilated for 5 h with low tidal volumes (LVT ~ 7.5 ml/kg) or high tidal volumes (HVT ~ 15 ml/kg) (VILI) (A). In addition, sRAGE (B) in BALF of WT mice in a 2-hit model of lipopolysaccharide (LPS) exposure followed by mechanical ventilation for 5 h with low tidal volumes (LVT ~ 7.5 ml/kg) or high tidal volumes (HVT ~ 15 ml/kg). Data represent mean (SEM) of n = 6 to 9 mice/group. **p < 0.01, and ***p < 0.001.