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. 2015 Dec 16;33(51):7283–7289. doi: 10.1016/j.vaccine.2015.10.111

Table 1.

Identification of possible epitopes. Computational analysis (http://www.mpiib-berlin.mpg.de/MAPPP/) of possible epitopes by C57BL/6 mice against the HIV transgene were cross-checked against the peptide sequence of individual peptides that were positive for IFN-γ production.

Transgene Peptide no. Peptide sequence Possible epitope Restriction
Gag 8 GTEELRSLYNTVATLYCVHE GTEELRSL/LRSLYNTVA H2Kb/H2Kb
17 EKAFSPEVIPMFTALSEGAT FSPEVIPMF/VIPMFTAL H2Kb/H2Kb
30 EPFRDYVDRFFKTLRAEQAT VDRFFKTLR H2Kb
31 FKTLRAEQATQEVKNWMTDT QEVKNWMTD H2Kb
Pol 5′ 32 GTVLVGPTPVNIIGR VGPTPVNII H2Db
69 ESFRKYTAFTIPSTN RKYTAFTI H2Kb
Nef 29 GKWSKSSIVGWPAVR KWSKSSIV/SIVGWPAV H2Kb/H2Kb
30 KSSIVGWPAVRERIR SIVGWPAV H2Kb
Pol 3′ 58 IVGAETFYVDGAANR GAETFYVD/AETFYVDG H2Kb/H2Kb
59 ETFYVDGAANRETKL AANRETKL H2Kb