Table 2.

Janus kinase and signal transducer and activator of transcription (JAK-STAT) pathway gene combinations associated with dairy traits.

Dairy trait	Gene combinations	P-value range∗
APR	SOCS1 + SOCS3 + CISH + IL6R + PRLR + STAT2 + IL2	<0.001–0.018
ASI	SOCS3 + JAK1 + IL10 + IL3 + IL2	<0.001–0.001
Protein yield	SOCS5 + CISH + STAT2 + IL3 + IL2	<0.001–0.004
Protein percentage	SOCS3 + SOCS4 + SOCS6 + SOCS7 + CISH + PRLR + STAT2 + IL10 + IL3	<0.001–0.046
Fat yield	SOCS1 + PRLR + IL4R + STAT1 + IL3	<0.001–0.004
Fat percentage	SOCS6 + STAT6 + PRLR + STAT2 + EPO + IL10	<0.001–0.036
Milk yield	SOCS3 + JAK1 + IL10 + IL3 + IL2 + JAK2	<0.001–0.032

^∗The range of P-values correspond to the results of 1000 permutations.