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. 2015 Dec 15;9:157. doi: 10.3389/fnana.2015.00157

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Copyright © 2015 Antón-Fernández, León-Espinosa, DeFelipe and Muñoz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A,B) Photomicrographs showing the patterns of hyperphosphorylated tau immunostaining (AT8 antibody) in the neocortex and hippocampus of control (A) and torpid (B) Syrian hamsters. Small squared zones in (B) are shown at higher magnification in (C,D). Note the AT8 immunostaining of layer V neuronal cell bodies (arrows in D) and their apical dendrites in layer III (arrows in C). The large squared zone in (B) and squared zone in (E) are shown at higher magnification in (E,F), respectively. Note the intense AT8 immunostaining in hylar neurons (arrows in F). Scale bar in F indicates 570 μm in (A,B), 57 μm in (C,D,F) and 115 μm in (E).