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. 2015 Dec;124:77–82. doi: 10.1016/j.antiviral.2015.10.006

Table 2.

Selectivity index. The selectivity index of each compound was calculated by dividing the CC50 by the IC50 value. IC50 values are for strain EV71 Genotype B2, Strain MS742387, taken from De Colibus et al. (2014), which was grown in Vero cells.

NLD GPP3 ALD
CC50 (Cell toxicity) 1600 nM 1000 nM 7000 nM
IC50 (Virus inhibition) 0.025 nM 0.39 nM 8.7 nM
Selectivity Index (CC50: IC50) 6 × 104 2.6 × 103 8 × 102