Table 2.
Selectivity index. The selectivity index of each compound was calculated by dividing the CC50 by the IC50 value. IC50 values are for strain EV71 Genotype B2, Strain MS742387, taken from De Colibus et al. (2014), which was grown in Vero cells.
NLD | GPP3 | ALD | |
---|---|---|---|
CC50 (Cell toxicity) | 1600 nM | 1000 nM | 7000 nM |
IC50 (Virus inhibition) | 0.025 nM | 0.39 nM | 8.7 nM |
Selectivity Index (CC50: IC50) | 6 × 104 | 2.6 × 103 | 8 × 102 |