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Patterns of reactivity in the DAT and associated types of AIHA (modified from [1])
| Reaction components | Type of AIHA |
|---|---|
| IgG alone | warm antibody AIHA |
| drug immune hemolytic anemia | |
| Complement alone | warm antibody AIHA with subthreshold IgG deposition |
| cold agglutinin disease | |
| paroxysmal cold hemoglobinuria | |
| drug-immune hemolytic anemia | |
| IgG plus complement | warm-antibody AIHA |
| mixed warm and cold antibody AIHA | |
| drug-immune hemolytic anemia | |
