Table 1.
Ref. | Year | n | DFI (mo) | Site of recurrence | Surgery | Associated procedure | Morbidity | Mortality | SPR | OS |
Dalla Valle et al[36] | 2006 | 1 | 18 | 1 panc remnant | 1 RP | Distal gastrectomy, segmentary resection of transverse colon, splenectomy, extended lymph node dissection | 0 | 0 | 24 | 42 |
Kleeff et al[35] | 2007 | 12 | 13 | 8 local 2 local + stomach 2 local + mesentery | 11 resection 1 partial gastrectomy | 4 IORT 1 right hemicolectomy | NA | NA | 13 | NA |
Koizumi et al[37] | 2010 | 2 | 83 28 | 2 panc remnant | 2 RP | / | NA | 0 | 10 8 | 93 36 |
Lavu et al[33] | 2011 | 8 | 27.5 | 8 panc remnant | 8 RP | 1 subtotal gastrectomy | (2/8) 25% | 0 | 15 | 74 |
Thomas et al[34] | 2012 | 7 | 41.1 | 1 abdominal wall 5 panc remnant 1 resection bed | 2 resection 5 RP | NA | NA | 0 | NA | 79.3 |
Kobayashi et al[38] | 2012 | 1 | 36 | 1 panc remnant | 1 RP | Partial pancreas autotransplantation | 0 | 0 | 20 | |
Boone et al[39] | 2013 | 10 | 25.3 | 3 resection bed 2 pancr remnant, small bowel 1 pancr remnant, colon 1 pancr remnant, small bowel, stomach 3 stomach | 3 resection pancreatic bed mass 4 RP 2 partial gastrectomy 1 SBR | 3 SBR 1 partial gastrectomy + splenectomy 1 partial colectomy | NA | 0 | 32.4 | 59.1 |
Miyazaki et al[4] | 2014 | 11 | 32 | 11 pancr remnant | 11 RP | 1 celicac resection + total gastrectomy 1 portal vein resection | (3/11) 27% | 0 | 25 | 78.2 |
Total | 62 | 27.5 (me) | / | 0 | 17.5 (me) | 66.55 (me) |
DFI: Disease free interval (from primary pancreatic resection); RP: Repeat pancreatectomy; SBR: Small bowel resection; SPR: Survival post-reoperation; OS: Overall survival after initial pancreatectomy; NA: Not applicable; me: Median; IORT: Intraoperative radiation therapy.