Table 3.
Primary tumour related complications in patients undergoing primary chemotherapy
| Ref. | % of patients requiring intervention for primary tumour related complications | Most common complication | Comment |
| Yun et al[18] (2014) | 3% | Obstruction > perforation | Mean onset of complications = 8 mo |
| Cetin et al[22] (2013) | 4% | Obstruction > rectovesical fistula | - |
| Muratore et al[46] (2007) | 6% | Obstruction > haemorrhage | - |
| Clements et al[45] (2009) | 8% | All obstruction | - |
| Scoggins et al[44] (1999) | 9% | All obstruction | Mean onset of complications = 3 mo |
| Poultsides et al[24] (2009) | 11% | Obstruction > perforation > pain | - |
| Seo et al[20] (2010) | 14% | Obstruction > bleeding | - |
| Benoist et al[26] (2005) | 15% | All obstruction | - |
| McCahill et al[16] (2012) | 16% | Obstruction > perforation, pain | Majority onset of complications < 12 mo |
| Michel et al[21] (2004) | 22% | All obstruction | Mean onset of complications = 4 mo |
| Yun et al[23] (2014) | 22% | Obstruction > perforation | Mean onset of complications = 7 mo |
| Matsumoto et al[19] (2014) | 26% | Majority obstruction | - |
| Ruo et al[43] (2003) | 29% | All obstruction | Majority onset of complications < 6 mo |
| Galizia et al[25] (2008) | 30% | Obstruction> perforation > haemorrhage | Mean onset of complication = 11 mo |
| Sarela et al[47] (2001) | 33% | Obstruction > pain > tenesmus | Mean onset of complication = 9 mo |
| Bajwa et al[27] (2009) | 40% | Obstruction > bleeding |