Figure 1.

Overall and active-site structure of jrTYR. A) The overall structure is shown as green cartoon with the four α-helical bundles forming the active site colored in red. B) The active site with the copper-coordinating histidine residues, blocker residue, and thioether bond are illustrated as stick models (green C, blue N, yellow S). The rest of the protein is shown as a green cartoon with 50 % transparency. The copper atoms are shown as brown spheres with the bridging solvent as a small red sphere.