Figure 2.

(A). Morphological changes of MCF-7 cells after treatment with auraptene, herniarin, umbelliferone, and umbelliprenin for 48 h. Control cells remained untreated and received an equal volume of the solvent. (B). Cytotoxic effects of auraptene, herniarin, umbelliferone, and umbelliprenin on MCF-7 cells. Cells were treated for 72 h with different concentrations of prenylated coumarins. Cytotoxicity was determined by MTT assay. Results are the mean ± SEM of three independent experiments. ∗p <0.05, ∗∗p <0.01, and ∗∗∗p <0.001 compared to control