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. 2015 Oct 5;54(48):14559–14563. doi: 10.1002/anie.201506592

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© 2015 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

© 2015 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Oligomerization of AMP in condensation buffer at 0 °C after 30 d. a) Reaction scheme. b) Ion-exchange HPLC chromatogram at λ_det=260 nm. c) Overlay of MALDI-TOF mass spectra of HPLC fractions, showing peaks of oligoribonucleotides with 2–9 residues.