Table 3.

De novo type 2 diabetes at follow-up of liver transplant recipients with NASH

	NASH w/o DM	Controls w/o DM	Relative risk (95 % CI)	p
Incidence of de novo DM at:
6 months follow-up	499 (19.2 %)	1,737 (13.9 %)	1.38 (1.26–1.51)	<0.0001
1 year follow-up	344 (14.3 %)	1144 (9.8 %)	1.46 (1.31–1.64)	<0.0001
3 years follow-up	186 (11.4 %)	560 (6.8 %)	1.67 (1.43–1.96)	<0.0001
5 years follow-up	73 (7.4 %)	275 (5.2 %)	1.43 (1.12–1.84)	0.0046
Had at least one onset of de novo post-transplant DM by:
1 year follow-up	624 (22.9 %)	2,196 (16.7 %)	1.37 (1.27–1.49)	<0.0001
3 years follow-up	578 (32.7 %)	2,004 (22.4 %)	1.46 (1.35–1.57)	<0.0001
5 years follow-up	425 (39.8 %)	1,548 (27.0 %)	1.47 (1.35–1.61)	<0.0001
Recorded resolution of post-transplant DM after the first onset	621 (73.8 %)	2,205 (74.7 %)	0.99 (0.94–1.03)	0.59
Time from onset to resolution, years	1.13 ± 1.06	1.07 ± 0.99		0.35
Long-term de novo post-transplant DM	174 (7.6 %)	481 (4.3 %)	1.76 (1.49–2.08)	<0.0001