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Inhibition of carnitine biosynthesis in HEK 293T cells.
| ||
|---|---|---|
| Compound | Concentration of compound [μM] | Carnitine levels* |
| AR692 | 100 | 52 ± 4 |
| AR692 | 300 | 33 ± 3 |
| AR692B | 100 | 57 ± 9 |
| AR780 | 50 | 21 ± 7 |
| AR780 | 10 | 40 ± 4 |
| Mildronate | 50 | 37 ±10 |
| Mildronate | 20 | 70 ± 6 |
Measured carnitine levels are given as percentage of free carnitine levels obtained for cells dosed with DMSO (control). Control was set to 100% (SEM ± 13%).
