Fig. 3.

Microscopic growth pattern following intracerebral and intra-arterial injection. a–c Microscopic tumor growth in the brain after intracerebral injection: representative GFP fluorescence images, histological brain sections stained for GFP, and fraction of mice showing microscopic growth at the injection site (a), in the ventricles (b), and in the leptomeninges (c). d–e Microscopic tumor growth in the brain after intra-arterial injection: representative fluorescence images showing growth of U-25 cells in the left lateral ventricle (d) and on the ventral surface of the brain (e). High magnification images (d–e) are shown as combined transillumination and pseudocolored fluorescence images. Arrow in d indicates corpus callosum