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. 2015 Dec 15;10:46. doi: 10.1186/s13027-015-0041-x

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© Santoro et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — CK19 staining expression and localization in perilesional mucosa in HPV⁻/HPV⁺ cancers. a. CK19 expression is evident in basal and intermediate layer in dysplasia surrounding HPV⁻OSCC. b. Strong expression of CK19 in a basaloid OPSCC. Note the overhead mucosa with CK19 up-regulation and maturation disturbance. (LSAB-HRP, nuclear counterstaining with haematoxylin; original magnification a, x200; b, x40)