Table 3.
Treatment characteristics of 125I seed implantation and outcomes (n = 10)
| No. | Metastasis | Size (cm) | Type of seeds implant | Seed activity (mCi) | No. of seeds/D90 (Gy) | Post-seed implant treatment | RR | LR (m) | Overall survival (m) | Causes of death |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Yes | 4.0 × 2.9 × 2.2 | CDU | 0.7 | 33/164.5 | No | CR | – | 107 | Survival |
| 1.3 × 1.5 × 1.0 | CDU | 0.7 | 6/148.1 | No | CR | – | ||||
| 2 | Yes | 4.0 × 3.6 × 1.8 | CDU | 0.8 | 50/172.7 | Seed implant after progress | PR | 24 | 70 | Survival |
| 2.5 × 2.0 × 2.0 | CDU | 0.7 | 8/169.4 | No | PR | – | ||||
| 1.8 × 1.2 × 1.0 | CDU | 0.65 | 9/171.6 | No | PR | – | ||||
| 3 | Yes | 6.6 × 7.8 × 9.5 | CT | 0.72 | 158/187.0 | No | PR | 12 | 14 | LR |
| 4 | No | 3.2 × 3.3 × 1.5 | CDU | 0.7 | 30/176.0 | No | CR | – | 62 | Survival |
| 3.4 × 3.0 × 1.2 | CDU | 0.77 | 35/166.1 | No | CR | – | ||||
| 5 | No | 3.2 × 2.9 × 2.0 | CDU | 0.8 | 54/174.9 | No | PR | – | 51 | Survival |
| 6 | No | 4.0 × 2.0 × 3.0 | CDU | 0.62 | 40/121.0 | No | PR | – | 41 | Survival |
| 7 | Yes | 3.8 × 3.5 × 3.0 | CT | 0.72 | 34/167.2 | EBRT (50Gy) | SD | 8 | 12 | MM |
| 8 | Yes | 3.5 × 4.9 × 12 | CT | 0.72 | 157/171.2 | No | PR | 3 | 6 | MM |
| 9 | Yes | 3.6 × 2.0 × 3.0 | CT | 0.66 | 27/132.0 | No | PD | 3 | 6 | MM |
| 10 | No | 5.8 × 2.8 × 5.0 | CT | 0.68 | 86/187.1 | No | PR | – | 7 | Survival |
Abbreviations: CDU color Doppler ultrasound guided, CT computed tomography guided, EBRT, external beam radiotherapy, RR response rate, CR complete response, PR partial response, SD stable disease, PD progressive disease, m months, LR local recurrence, MM multiple metastasis