Table 1.

Effect of PDTC on the percentage of viable HK-2, WT9-7 and WT9-12 cells, assessed by MTT assay after 6 h, 24 h and 48 h of treatment

	HK-2	WT9-7	WT9-12
6 h
Control	100 ± 19.0	100 ± 10.2	100 ± 13.9
5 μM	99.6 ± 8.5	110 ± 26.8	103.0 ± 9.8
20 μM	98.8 ± 9.2	120.2 ± 13.1	97.1 ± 7.8
50 μM	76.8 ± 13.5	43.4 ± 9.3 **	87.6 ± 14.1
24 h
Control	100 ± 15.0	100 ± 8.8	100 ± 12.6
5 μM	105.8 ± 7.7	85.2 ± 20.1	97.8 ± 14.3
20 μM	112.2 ± 7.6	103.6 ± 27.3	99.9 ± 9.1
50 μM	42.7 ± 2.8 **	17.1 ± 7.7 **	72.9 ± 5.9 **
48 h
Control	100 ± 9.6	100 ± 13.3	100 ± 5.9
5 μM	76.9 ± 7.1 **	50.4 ± 11.7 **	75.9 ± 8.4 **
20 μM	90.3 ± 10.9	91.7 ± 24.0	82.1 ± 8.0 **
50 μM	19.3 ± 2.0 **	6.0 ± 0.5 **	51.7 ± 9.2 **

Data are expressed as mean ± SD from n = 8 wells. **p < 0.01 vs. untreated control for the same cell line at the corresponding timepoint