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. 2015 Dec 15;16:212. doi: 10.1186/s12882-015-0193-3

Table 3.

Summary of the main findings of this study

HK-2 WT9-7 WT9-12
Pattern of serum-induced proliferation Increased in a time-dependent manner Same pattern as HK-2 cells Same pattern as HK-2 cells
Effect of PDTC on proliferation Reduced at 4-24 h Reduced at 8-24 h Reduced at 24 h
Endogenous NF-κB reporter activity High Moderate Low
Effect of exogenous LPS on NF-κB reporter activity Increased No change No change
Effect of exogenous TNF-α on NF-κB reporter activity Increased Increased Increased
Effect of PDTC on TNF-α-induced NF-κB reporter activity Reduced No change No change
Effect of PDTC on TNF-α-induced nuclear NF-κB protein levels Reduced p50 Reduced p50 Reduced p50
Effect of exogenous LPS and TNF-α on proliferation at 4 h and 24 h Same as unstimulated cells Same as unstimulated cells Same as unstimulated cells