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. 2015 Nov 17;43(22):11061–11067. doi: 10.1093/nar/gkv1255

Figure 2.

Figure 2.

S. aureus Trx structure and kinetic values of indicated variants. (A) The Trx structure (taken from (29)) is shown in the cartoon representation with the highlighted residues. Trp28 forms an H bond with Asp58 and participates in deprotonation of Cys29 to form the active thiolate. The oxidized Trx with a Cys29—Cys32 disulfide bond is shown. (B) The reaction velocities of the Trx enzymes Trp28 (WT), Bta28 and Ala28 are plotted against the substrate concentration of oxidized ArsC.