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. 2015 Nov 19;43(22):10804–10820. doi: 10.1093/nar/gkv1262

Figure 2.

Figure 2.

Interpretation of TSEA plots. (A) The dendrogram skeleton depicts an approximation of a hierarchical clustering of the tissues based on gene expression. (B) The outer white hexagon's size is proportional to the number of transcripts enriched in a particular tissue at the least stringent threshold of pSI <0.05. (C) The size of the gray concentric hexagons is proportional to the number of transcripts enriched in a particular tissue at the more stringent threshold (0.001, 0.001, 0.0001 from outermost to innermost). (D) A heatmap color scheme is added ot the appropriate hexagon to depict the significance of the Fisher's Exact test. Note, any significance in the outermost hexagon is hashed to reflect that the transcript lists at this threshold are less specific. The results shown here highlight the enriched expression of the 69 genes associated with the GO term ‘Glycogen Metabolic Process’ in multiple relevant tissues.