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. 2015 Sep 17;43(22):10760–10781. doi: 10.1093/nar/gkv934

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© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 7. — Silencing of CITED2 reduces both chromatin relaxation and H3Ac/p53 complex loading on the ERCC1 promoter. (A) Reduction of chromatin relaxation markers following CITED2 silencing. HEK293 cells receiving the indicated treatments were processed for immunoblotting. (B) Enhanced p53 binding to the ERCC1 promoter following treatment with TSA. (C) Quantification of enhanced p53 binding to the ERCC1 promoter by TSA shown in (B). (D) Suppression of H3K9Ac/p53 binding to ERCC1 promoter by shCITED2. (E) Suppression of H3K14Ac/p53 binding to ERCC1 promoter by shCITED2.