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. 2015 Dec 15;5:18147. doi: 10.1038/srep18147

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Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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The MCC tree was obtained by performing Bayesian MCMC analysis of the concatenated CRF01_AE (Regions I + III + V) (A) and the subtype B region (Regions II + IV) (B), using a relaxed clock model in GTR + G4 with a constant coalescent model. Analyses were implemented in BEAST v.1.6.0. HIV-1 subtype C sequences are used as an outgroup. The medians of tMRCAs with 95% highest probability density (HPD) (in parenthesis) and the posterior probability ( > 0.95) of the nodes relevant to this study were shown. (C) The distribution of the posterior probability of the estimated tMRCAs for CRF55_01B and related lineages: CRF01_AE lineages (top) and subtype B lineage (bottom).