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. Author manuscript; available in PMC: 2015 Dec 15.
Published in final edited form as: Mol Pharmacol. 2012 Aug 6;82(5):887–897. doi: 10.1124/mol.112.081133

Fig. 3.

Fig. 3

Nrf2 suppresses the induction of TXNIP by diabetes in mouse heart. Adult male WT and KO mice were treated with STZ to induce diabetes. Heart tissues were collected as described for Fig. 1, immunoblotting. Heart homogenate was immunoblotted for Nrf2 (A) or TXNIP (B) and quantified. Actin was blotted for loading variation. C, immunofluorescent staining. Heart sections were stained with anti-TXNIP and green fluorescence. DAPI was used to stain for nuclei. D, quantification of TXNIP immunofluorescence intensity from C. Data represent means and S.D. from four to six samples. *, p < 0.05; **, p < 0.01; ***, p < 0.001.