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TXNIP mediates glucose-induced apoptosis in H9C2. Cells were treated as described for Fig. 7. A, apoptosis measured for caspase 3/7 activity as luminescence intensity using Caspase-Glo. B, apoptosis measured for PhiPhiLux G1D2-positive cells (percentage) using multiparameter flow cytometry. Data represent means and S.D. from three to six samples. **, p < 0.01.
