Table 4.
Agreement of Antibody Testing With Real-Time Polymerase Chain Reaction Results During an Outbreak of Chlamydia pneumoniae in a Federal Correctional Facility, Among Samples From Inmates With and Without Acute Respiratory Illnessa
| C. pneumoniae qPCR Result | Single IgM ≥1:10 | Single IgG ≥1:512 | 4-Fold Increase in IgG |
|---|---|---|---|
| No ARI | |||
| qPCR-positive (n = 1) | 0/1 (0%) | 1/1 (100%) | 0/0 |
| qPCR-negative (n = 37) | 7/37 (18.9%) | 23/37 (62.2%) | 0/1 (0%) |
| ARI | |||
| qPCR-positive (n = 25) | 21/25 (84.0%) | 24/25 (96.0%) | 4/10 (40.0%) |
| qPCR-negative (n = 59) | 17/59 (28.8%) | 35/59 (59.3%) | 2/22 (9.1%) |
Results shown are the number positive/number tested (%).
Abbreviations: ARI, acute respiratory illness; IgG, immunoglobulin G; IgM, immunoglobulin M; qPCR, real-time polymerase chain reaction.
a
ARI defined as follows: cough lasting ≥3 days AND 1 or more of the following: myalgias, headache, sore throat; OR fever ≥37.2°C or chills AND 1 or more of the following: myalgias, headache, sore throat, cough ≥3 days.