Fig. S4.

Associative selectivity in novel and familiar blocks. (A) ROC values in both individual novel blocks for neurons that were recorded for two novel blocks (n = 53), confirming that selectivity was largely similar across blocks. (B) Histogram of ROC values in familiar blocks, as in Fig. 4A. (C) Comparison of ROC values in novel blocks during learning and after learning, as in Fig. 4A, but for all recorded neurons, regardless of selectivity in familiar blocks. Significant difference: **P < 0.01. (D) Individual neurons’ ROC values in familiar blocks, and change in ROC values during novel blocks, confirming that prospective responses are driven by familiar-selective neurons. Red dots indicate neurons with significant selectivity in familiar blocks, analyzed in Figs. 4 and 5.