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. 2015 Nov 2;112(49):15154–15159. doi: 10.1073/pnas.1517584112

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Fig. 4. — MYD88 and UNC93b control GSAT i-ncRNA stimulation. Genetic screen of the innate immune pathway related to i-ncRNA function in murine imBMs. The imBM cells of different genotypes (WT, MYD88 KO, and UNC93b^3d/3d MUT) have been stimulated by liposomal transfection (DOTAP liposomal transfection reagent) of the murine i-ncRNA (GSAT). TNF-alpha (TNF-a) production in the supernatant has been quantified, and each point represents the mean value of the experimental replicates for each individual condition; the bar represents the median. *P < 0.05.