Table S2.
Pathway name (Ingenuity) | P | No. of molecules |
Cell death and survival | 7.11−30 to 4.65−07 | 48 |
Cellular development | 2.62−17 to 4.54−07 | 42 |
DNA replication, recombination, and repair | 5.65−17 to 4.54−08 | 20 |
Cell cycle | 7.09−17 to 2.75−07 | 30 |
Cellular growth and proliferation | 1.35−16 to 3.36−07 | 46 |
Listed are the top ranking components of the Global Canonical Pathway (GCP) category after pathway analysis (Ingenuity), pathway names and involved molecules defined by Ingenuity) of the miR-3151 associated gene expression signature. The P value associated with a pathway in GCP is a measure of the likelihood that the association between a set of focus genes in the analyzed experiment and a given pathway is due to random chance. The P value identifies statistically significant overrepresentation of focus genes in a given process. It is automatically calculated by the ingenuity pathway analysis program (ingenuity.com) using the right-tailed Fisher’s exact test.