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. 2015 Nov 18;112(49):E6744–E6751. doi: 10.1073/pnas.1520390112

Table S2.

Molecular and cellular functions predicted to be influenced by miR-3151 (Ingenuity)

Pathway name (Ingenuity) P No. of molecules
Cell death and survival 7.11−30 to 4.65−07 48
Cellular development 2.62−17 to 4.54−07 42
DNA replication, recombination, and repair 5.65−17 to 4.54−08 20
Cell cycle 7.09−17 to 2.75−07 30
Cellular growth and proliferation 1.35−16 to 3.36−07 46

Listed are the top ranking components of the Global Canonical Pathway (GCP) category after pathway analysis (Ingenuity), pathway names and involved molecules defined by Ingenuity) of the miR-3151 associated gene expression signature. The P value associated with a pathway in GCP is a measure of the likelihood that the association between a set of focus genes in the analyzed experiment and a given pathway is due to random chance. The P value identifies statistically significant overrepresentation of focus genes in a given process. It is automatically calculated by the ingenuity pathway analysis program (ingenuity.com) using the right-tailed Fisher’s exact test.