Table 3.
Simulation results. Estimates taken over 1000 generated datasets. Each dataset has 
observations. True values for the intercept and the coefficient of 
are 
and 
, respectively
|
Intercept |
Coefficient |
|||||||
|---|---|---|---|---|---|---|---|---|
| Method | MSE | Bias | SE | % Coverage | MSE | Bias | SE | % Coverage |
| Correct censoring and outcome model variables | ||||||||
| IPCW | 13.6 | 1.4 | 119.6 | 95.9 | 25.3 | 1.1 | 169.6 | 96.0 |
| SAR | 13.5 | 2.7 | 108.9 | 93.5 | 24.5 |
 1.1 |
152.5 | 94.7 |
| TMLE-BIN | 13.3 | 1.7 | 110.6 | 94.7 | 24.3 | 0.8 | 154.3 | 95.3 |
| Misspecified censoring, correct outcome model variables | ||||||||
| IPCW | 18.0 |
 74.0 |
110.2 | 89.7 | 29.1 |
 66.0 |
158.2 | 93.7 |
| SAR | 12.8 | 1.9 | 104.7 | 94.0 | 23.7 | 0.0 | 150.6 | 94.7 |
| TMLE-BIN | 12.6 | 2.6 | 104.7 | 94.7 | 23.6 |
 2.1 |
150.6 | 94.4 |
| Misspecified outcome, correct censoring model variables | ||||||||
| IPCW | 13.6 | 1.4 | 119.6 | 95.9 | 25.3 | 1.1 | 169.6 | 96.0 |
| SAR | 13.8 | 9.6 | 111.8 | 94.9 | 25.5 |
 2.5 |
155.7 | 94.6 |
| TMLE-BIN | 13.6 |
 0.2 |
114.6 | 94.9 | 24.9 | 3.3 | 158.9 | 95.3 |
| Misspecified censoring and outcome model variables | ||||||||
| IPCW | 18.0 |
 74.0 |
110.2 | 89.7 | 29.1 |
 66.0 |
158.2 | 92.7 |
| SAR | 14.5 |
 38.1 |
105.1 | 91.1 | 23.6 | 9.5 | 151.0 | 94.6 |
| TMLE-BIN | 25.6 |
 117.0 |
106.4 | 80.5 | 23.3 | 24.5 | 152.1 | 94.6 |
| TMLE-SL(all) | 12.6 |
 11.4 |
100.8 | 92.9 | 23.4 | 9.2 | 143.9 | 93.7 |
| TMLE-SL(adapt) | 13.6 |
 32.4 |
96.4 | 89.1 | 23.4 | 14.1 | 136.5 | 92.1 |
| TMLE-SL(par) | 12.7 |
 11.3 |
104.7 | 93.9 | 23.5 | 7.5 | 150.4 | 94.7 |
All values (except coverage) are given as 
.
MSE: mean squared error; SE: the square-root of the mean sandwich estimator variance; TMLE-BIN:TMLE with logistic regressions for censoring and outcome models; TMLE-SL: TMLE with Super Learner, (all) with the complete SL library, (adapt) with only main terms logistic regression in addition to the adaptive methods, and (par) with only logistic regression implementations.