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. Author manuscript; available in PMC: 2016 Dec 17.
Published in final edited form as: Neuroscience. 2015 Nov 5;311:499–507. doi: 10.1016/j.neuroscience.2015.10.059

Figure 3. Local effect of TTX on ergonomic injury-induced mechanical hyperalgesia.

Figure 3

After assessment of the mechanical nociceptive threshold (Baseline), rats were submitted to an eccentric exercise protocol. Twenty-four hours later, rats exhibited significant mechanical hyperalgesia (Pre). The local treatment (Post) with a dose of 1 μg of TTX, but not of D-PBS (Vehicle), markedly attenuated the eccentric exercise-induced muscle mechanical hyperalgesia. ***P < 0.001.