Table 5.
Association of baseline characteristics with major amputation and mortality in Rutherford category IV.
| Univariate analysis | Multivariate analysis | |
|---|---|---|
| Patient characteristics | ||
| Age | 1.0 (1.0, 1.0) | – |
| >80 years | 1.0 (0.6, 1.9) | – |
| <70 years | 1.2 (0.7, 2.2) | – |
| <60 years | 1.0 (0.3, 3.1) | – |
| Male gender | 1.1 (0.6, 1.9) | – |
| BMI < 18.5 kg/m3 | 3.4 (1.8, 6.3)**** | 2.7 (1.4, 5.4)*** |
| Non-ambulatory | 2.1 (1.1, 3.9)* | 3.0 (1.5, 5.9)*** |
| Albumin < 3.0 g/dL | 3.1 (1.6, 6.3)*** | 2.0 (0.9, 4.4) |
| CRP > 3.0 mg/dL | 3.1 (1.5, 6.3)*** | 2.8 (1.2, 6.5)* |
| Hypertension | 1.4 (0.7, 2.8) | – |
| Dyslipidemia | 0.6 (0.3, 1.0) | – |
| Diabetes mellitus | 0.9 (0.5, 1.6) | – |
| End stage of renal disease | 1.8 (1.0, 3.1)* | 1.3 (0.7, 2.4) |
| Current smoking | 1.2 (0.7, 2.1) | – |
| COPD | 2.9 (1.2, 6.8)* | 2.9 (1.2, 7.1)* |
| CAD | 2.1 (1.2, 3.6)** | 2.6 (1.5, 4.7)*** |
| CVD | 1.5 (0.8, 2.7) | – |
| Statin | 0.5 (0.2, 1.0)* | 0.5 (0.2, 1.1) |
| Lesion characteristics | ||
| BTK lesion length | 1.0 (1.0, 1.0) | – |
| CTO | 1.7 (0.9, 3.2) | – |
| BTK run-off vessels | 1.0 (0.8, 1.4) | – |
| BA disease | 0.8 (0.6, 1.1) | – |
| Procedure success | ||
| Success | 2.4 (0.3, 17.4) | – |
Data are hazard ratios and 95% confidence intervals.
BMI: body mass index; CRP: C-reactive protein; COPD: chronic obstructive pulmonary disease; CAD: coronary artery disease; CVD: cerebral vascular disease; BTK: below-the-knee; CTO: chronic total occlusion; BA: below-the-ankle.
*
p < 0.05; **p < 0.01; ***p < 0.005; ****p < 0.0005.