Agarwal 2000.

Methods	Parallel‐group randomized trial, conducted in India. Study dates not reported.
Participants	200 people undergoing endoscopic urological surgery. Exclusion: patient refusal to participate in study, previous history of PONV and motion sickness, impaired renal function with increased urea and creatinine concentrations, diabetes mellitus, obesity, patients receiving antiemetic medication, histamine H₂ receptor antagonist within 72 hours of surgery. No participant withdrew from the study.
Interventions	Acupressure wristband placed at P6 points on both forearms, applied 30 min before induction of anaesthesia and removed after 6 hours following surgery (n = 100). Sham group was the spherical bead of acupressure wristbands placed on posterior surface, applied 30 min before induction of anaesthesia and removed 6 hours after surgery (n = 100).
Outcomes	Nausea (0 ‐ 24 h), vomiting (0 ‐ 24 h), side effects of acupressure, risk of rescue antiemetic drug.
Notes	Rescue antiemetic was ondansetron 4 mg IV. No side effects or complications noted in either group. No details about funding source or any declarations of interest among authors.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	"Patients were assigned to two different groups according to a computer‐generated table of random numbers".
Allocation concealment (selection bias)	Unclear risk	Insufficient information.
Blinding of patients (performance bias) All outcomes	Unclear risk	Insufficient information.
Blinding of healthcare providers (performance bias) All outcomes	Unclear risk	Insufficient information.
Blinding of outcome assessor (detection bias) All outcomes	Low risk	"An anesthesiologist blinded to the therapy registered the incidence of nausea and vomiting at three different times in the first 24 hr postoperatively: on arrival of the patient in PACU, and at six hours (time of removal of acupressure wristband) and 24 hr after operation".
Incomplete outcome data (attrition bias) All outcomes	Low risk	"No patient was excluded after admission to the study".
Selective reporting (reporting bias)	Low risk	All expected outcomes reported.
Other bias	Low risk	Baseline characteristics were comparable: "Patients were comparable in both the groups as regards to age, sex, height and weight".