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. 2015 Nov 2;2015(11):CD003281. doi: 10.1002/14651858.CD003281.pub4

Butkovic 2005.

Methods Parallel‐group randomized trial, conducted in Croatia. Study dates not reported.
Participants 120 children (5 ‐ 14 years) undergoing hernia repair, circumcision, or orchidopexy.
 Exclusion: children predisposed to nausea and vomiting secondary to gastroesophageal reflux, motion sickness, and inner ear or central nervious system disorders.
Interventions Group 1: laser acupuncture on P6 acupoint bilaterally for 1 min, 15 min before induction of anaesthesia and IV infusion of saline (n = 40).
Group 2: metoclopramide 0.15 mg/kg IV and sham laser on P6 acupoint bilaterally for 1 min, 15 min before induction of anaesthesia (n = 40).
Group 3: sham laser stimulation on P6 acupoint bilaterally for 1 min, 15 min before induction of anaesthesia and saline infusion (n = 40).
Outcomes Vomiting (0 ‐ 2 h), risk of rescue antiemetic drug.
Notes Rescue antiemetic was ondansetron 0.1 mg/kg IV if vomiting was severe. No details about funding source or any declarations of interest among authors.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Insufficient information.
Allocation concealment (selection bias) Unclear risk Insufficient information.
Blinding of patients (performance bias) 
 All outcomes Low risk Authors took adequate steps to make intervention appear similar.
Blinding of healthcare providers (performance bias) 
 All outcomes Low risk "Researchers were double‐blinded" but no specific details about how blinding was achieved. Comment: probably done.
Blinding of outcome assessor (detection bias) 
 All outcomes Low risk "Researchers were double‐blinded" but no specific details about how blinding was achieved. Comment: probably done.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No missing data reported for the 120 children analysed.
Selective reporting (reporting bias) High risk Description of side effects not included. Nausea not reported because it may be difficult to assess in children.
Other bias Low risk Baseline characteristics were comparable. "Demographic data showed no significant difference among groups".