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. 2015 Nov 2;2015(11):CD003281. doi: 10.1002/14651858.CD003281.pub4

Duggal 1998.

Methods Parallel‐group randomized trial, conducted in Canada. Study dates not reported.
Participants 263 women undergoing spinal anaesthesia for elective Caesarean delivery.
 Excluded: women with a history of hyperemesis gravidarum or if they had received antiemetic medication during the 48 h before surgery. 8 women excluded for failing to wear wristbands for 10 hours, 3 had received prophylactic antiemetics, and 8 were not given standard combination of intrathecal drugs (total 19 withdrawals).
Interventions Acupressure wristbands were applied to both wrists just before induction of spinal anaesthesia and worn for 10 hours (n = 122).
Sham acupressure wristbands were applied at P6 acupoint (but stud missing) on both wrists just before induction of spinal anaesthesia and worn for 10 hours (n = 122).
Outcomes Nausea (0 ‐ 10 h), vomiting (0 ‐ 10 h), risk of rescue antiemetic (type of drug not given), side effects of acupressure. Patients recorded outcome measures on a questionnaire.
Notes Adverse effects of acupressure wristbands: tightness, swollen hands, problems with infusion, itching wrists. Intraoperative nausea and vomiting reported.
Funding by a grant from the BC Medical Services Foundation. Wristbands were donated by Sea Band UK Ltd. No details of any declarations of interest among the authors.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk "A table of random numbers was used to allocate patients to one of two groups".
Allocation concealment (selection bias) Unclear risk Insufficient information.
Blinding of patients (performance bias) 
 All outcomes Low risk "The nature of the bands was therefore unknown to the patient, anaesthetist and investigators for the duration of the study".
Blinding of healthcare providers (performance bias) 
 All outcomes Low risk "The nature of the bands was therefore unknown to the patient, anaesthetist and investigators for the duration of the study".
Blinding of outcome assessor (detection bias) 
 All outcomes Low risk "The nature of the bands was therefore unknown to the patient, anaesthetist and investigators for the duration of the study".
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Reasons for withdrawals were given. No missing data reported for the 244 participants analysed.
Selective reporting (reporting bias) Low risk All expected outcomes reported.
Other bias Low risk Baseline characteristics were comparable. "Demographic analysis revealed no statistically significant difference between subjects in the two groups".